Feb 01, 2002 · The willingness to accept adult neurogenesis was further enhanced by the convincing evidence that fetal tissue could be grafted in the adult intact brain. Even more convincing was the evidence that the damaged adult brain and spinal cord allowed these newly grafted cells to survive and differentiate (Bjorklund and Gage, 1985).Cited by: 1009. Nov 01, 1998 · The genesis of new cells, including neurons, in the adult human brain has not yet been demonstrated. This study was undertaken to investigate whether Cited by: 6935.
May 26, 2011 · Adult neurogenesis, a process of generating functional neurons from adult neural precursors, occurs throughout life in restricted brain regions in mammals. The past decade has witnessed tremendous progress in addressing questions related to almost every Cited by: 2213. Neurogenesis in the Adult Brain Fred H. Gage Laboratory of Genetics, The Salk Institute, La Jolla, California 92037 A milestone is marked in our understanding of the brain with the recent acceptance, contrary to early dogma, that the adult ner-vous system can Cited by: 1009.
May 31, 2019 · Moreover, adult neurogenesis was shown to occur in limited areas of the brain, and the number of new neurons being generated was clearly small. In the 1990s, adult neurogenesis was investigated in more species, including non-human primates and humans. However, attention was turning away from questioning whether adult neurogenesis occurred, and Cited by: 5. Because it has turned out that adult neurogenesis not only exists in the human hippocampus but even seems to be restricted to it (see Spalding et al. 2013; Bergmann et al. 2015), public and scientific attention to the phenomenon is soaring.In PubMed, search results for “adult neurogenesis” and “hippocampus” outnumber those for “adult neurogenesis” and “olfactory bulb” or Cited by: 488.
Adult neurogenesis is the process by which neurons are generated from neural stem cells in the adult. This process is different from the embryonic development of neurogenesis.. In most mammals, new neurons are continually born throughout adulthood in two regions of the brain: The subgranular zone (SGZ), part of the dentate gyrus of the hippocampus, where neural stem cells give birth to granule. Nov 03, 2016 · Electronic address: [email protected] The dentate gyrus of the mammalian hippocampus continuously generates new neurons during adulthood. These adult-born neurons become functionally active and are thought to contribute to learning and memory, especially during their maturation phase, when they have extraordinary plasticity.Cited by: 335.